Speaker: Dr. Casey Paquola (PI of Multiscale Neuroanatomy Lab in the Institute for Neuroscience and Medicine (INM-1) at the Forschungszentrum Jülich)
Date: Thursday 12 May 2022
Time: 15-17 h (CET or GMT +01:00, i.e. Amsterdam, Paris, Berlin).
Location: hybrid lecture. Zoom link: https://radbouduniversity.zoom.us/j/82567407459?pwd=UmE4ck05d3BOVU9YMi9ncXd2ZUNJQT09
Conceptualising the Cortex
Many fields depend on neuroanatomy to define good models of brain organisation. Concise neuroanatomical descriptions are essential to ensure that brain-based accounts are plausible (e.g. of cognition, development or disease). Yet, current implementations tend to be focused on an oversimplified conception of the cortex as a mosaic. I'll discuss the history of area-based modularity and what is neglected by the mosaic concept. I propose a shift towards a multi-dimensional depiction of the cortex, which incorporates fine-grained differentiation on the one hand with large-scale axes on the other. I'll demonstrate how such multi-dimensional approaches can effectively incorporate diverse information of the cortex into a single cohesive model. Furthermore, I'll provide several examples of how a multi-scale depiction of the cortex benefits neuroscientific investigations, such as characterising the cognitive roles of brain networks (specifically the default mode network) or understanding how the cortex develops.
Dr Casey Paquola leads the Multiscale Neuroanatomy Lab in the Institute for Neuroscience and Medicine (INM-1) at the Forschungszentrum Jülich. Previously, she obtained a PhD in Medicine from the University of Sydney in the lab of Maxwell Bennett, and undertook a postdoctoral fellowship at the Montreal Neurological Institute in the lab of Boris Bernhardt. With a background in neuroscience and the history and philosophy of science, she aims to develop theories on how the cellular organisation of the human brain gives rise to complex functional dynamics. Her recent research is inspired by working at the interface of microscopy, neuroimaging and computational modelling, as she demonstrates the potential of multi-modal approaches to uncover fundamental principles of brain organisation.
For more information about The Dutch Distinguished Lecture Series in Philosophy and Neuroscience and the program of talks for this semester, please click here.
Organiser(s): Daniel Kostic, Henk de Regt, Leon de Bruin, Marc Slors, Peter Hagoort, Gerrit Glas and Linda Douw
Date: Thursday 12 May 2022
Time: 15-17 h (CET or GMT +01:00, i.e. Amsterdam, Paris, Berlin).
Location: hybrid lecture. Zoom link: https://radbouduniversity.zoom.us/j/82567407459?pwd=UmE4ck05d3BOVU9YMi9ncXd2ZUNJQT09
Conceptualising the Cortex
Many fields depend on neuroanatomy to define good models of brain organisation. Concise neuroanatomical descriptions are essential to ensure that brain-based accounts are plausible (e.g. of cognition, development or disease). Yet, current implementations tend to be focused on an oversimplified conception of the cortex as a mosaic. I'll discuss the history of area-based modularity and what is neglected by the mosaic concept. I propose a shift towards a multi-dimensional depiction of the cortex, which incorporates fine-grained differentiation on the one hand with large-scale axes on the other. I'll demonstrate how such multi-dimensional approaches can effectively incorporate diverse information of the cortex into a single cohesive model. Furthermore, I'll provide several examples of how a multi-scale depiction of the cortex benefits neuroscientific investigations, such as characterising the cognitive roles of brain networks (specifically the default mode network) or understanding how the cortex develops.
Dr Casey Paquola leads the Multiscale Neuroanatomy Lab in the Institute for Neuroscience and Medicine (INM-1) at the Forschungszentrum Jülich. Previously, she obtained a PhD in Medicine from the University of Sydney in the lab of Maxwell Bennett, and undertook a postdoctoral fellowship at the Montreal Neurological Institute in the lab of Boris Bernhardt. With a background in neuroscience and the history and philosophy of science, she aims to develop theories on how the cellular organisation of the human brain gives rise to complex functional dynamics. Her recent research is inspired by working at the interface of microscopy, neuroimaging and computational modelling, as she demonstrates the potential of multi-modal approaches to uncover fundamental principles of brain organisation.
For more information about The Dutch Distinguished Lecture Series in Philosophy and Neuroscience and the program of talks for this semester, please click here.
Organiser(s): Daniel Kostic, Henk de Regt, Leon de Bruin, Marc Slors, Peter Hagoort, Gerrit Glas and Linda Douw